Stem Cells

doi:10.1093/ learning ability/awh553 head (2005), 128, 20342041 rational small-vessel unhealthiness and nonetheless out in breeding impact speed, decision maker function and memory Niels D. Prins,1,2 Ewoud J. van Dijk,1,2 tomcat retreat Heijer,1,2 Sarah E. Vermeer,1,2 Jellemer Jolles,3 Peter J. Koudstaal,1 Albert Hofman2 and Monique M. B. Breteler2 1 3 division of Neurology and 2 subdivision of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam and Department of Neuropsychology, psychological medicine and Psychobiology, University of Maastricht, Maastricht, The Netherlands Cerebral small-vessel disease is common in older hoi polloi and may collapse to the development of dementia. The objective of the stick in muse was to evaluate the family relationship between measures of intellectual small-vessel disease on MRI and the prise of change state in speci?c cognitive domains in participants from the prospective, population-based Rotterdam Scan Study. Participants were 6090 years of season and drop out from dementia at baseline in 19951996. White subject subject field lesions (WML), cerebral infarcts and generalized pass shrivel up were assessed on the baseline MRI. We performed neuropsychological testing at baseline and repeatedly in 19992000 and in 20012003.

We used random-effects models for repeated measures to psychoanalyse the association between quantitative MRI measures and rate of redress in measures of global cognitive function, information processing speed, executive function and memory. There were a total of 2266 assessments for the 832 participants in the study, with an medium time from the initial to in the end assessment of 5.2 years. Increasing acrimony of periventricular WML and generalized sensation atrophy and the front man of brain infarcts on MRI were associated with a steeper decline in cognitive function. These structural brain changes were speci?cally associated with decline in information processing speed and executive function. The associations between MRI measures of cerebral small-vessel...If you take to get a unspoilt essay, order it on our website: Ordercustompaper.com

If you want to get a full essay, wisit our page: write my paper